Guided bone generation (GBR) is one of popular method to augment bone defect associated with implant placement. Resorbable or non-resorbable membrane is required to exclude soft tissue ingrowth into the bone graft for successful GBR. Variable platelet concentrates have been introduced to accelerate new bone formation. Recently autologous fibrin rich block with concentrated growth factors (CGF) was introduced by Dr. Sacco in 2006. CGF doesn’t require any chemical or allergenic additives, such as bovine thrombin or anticoagulants unlike PRP and PRGF, so it is free from viral transmission disease. CGF barrier can be used as alternatives to resorbable membrane in GBR and bone graft in sinus augmentation, and it accelerates new bone formation.
Compressed CGF can be used barrier membrane with growth factors as alternative collagen membrane. This barrier induces faster formation and soft tissue healing. When it is mixed with bone graft, faster bone formation can be obtained.
When CGF is applied to donor site of connective tissue graft, it reduces pain and inflammation and bleeding tendency. In addition, faster soft tissue healing can be obtained. CGF can be applied for sinus augmentation to induce faster new bone formation too.